Your answers must be in the discussion board (not an attachment) to facilitate class discussion. The grade will be a zero if the answers are not in the discussion board post. The initial post is due Sunday, 3/24/24 at 8 PM. Response to a classmate is due 3/26/24 at 8 PM.
Please provide citations when answering the following case study. At least two references are present (text, outside scholarly source less than five years old). See the attached rubric.
A 65-year-old previously well man presents to the clinic with complaints of fatigue of 3 months’ duration. Questioning reveals diffuse weakness and feeling winded when walking uphill or climbing more than one flight of stairs. All symptoms have slowly worsened over time. There are no other complaints, and the review of systems is otherwise negative. The patient has no significant medical history, social history, or family history. On physical examination, he appears somewhat pale, with normal vital signs. The physical examination is unremarkable except for his rectal examination, which reveals brown, guaiac-positive stool (suggesting the presence of blood in the stool). A blood test reveals anemia.
1. What is the most likely form of anemia in this man? What is the probable underlying cause?
2. What is the mechanism by which this disorder results in anemia?
3. What might one expect to see in the peripheral blood smear?
4. What other tests might be ordered to confirm the diagnosis?
5. What is the pathophysiologic mechanism of this patient’s fatigue, weakness, and shortness of breath? Why is he pale?
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