PICOT: In young adults, how effective are health screenings at age 45 compared t

PICOT: In young adults, how effective are health screenings at age 45 compared to the old, recommended age of 50 in the incidence of Colorectal Cancer over the past 10-20 years?
This is the topic I chose, and I have already found some articles and started on the paper; you can change whatever needs to be changed. I mainly want the chart completed. I attached the review method and matrix guidelines and what I have done also.