You will prepare ONE document for this assignment. Include your answers for both Part 1 & Part 2 on the same document before uploading your assignment for grading. APA formatting is NOT required for this assignment.
Part 1
For some rare autosomal dominant diseases, it is possible that the dominant homozygote has never been seen. One reason is that the fetus with this genotype may die early in development and be spontaneously aborted. In fact, roughly 25% of all women will have a pregnancy end in spontaneous abortion at some point during their lifetimes.
Consider a situation in which:
Q/Q dies as an early fetus ____________
Q/q lives to reproduce but is unaffected _____________
q/q lives and is unaffected _________________
What genotypes are possible among live-born children of the mating Q/q × Q/q?
(Hint: Construct a 2 by 2 table to reflect the genotypes of the parents as shown on pp. 531-533)
Note: Rewrite the situations above on your paper and add only your answers as indicated by the blanks after each situation. Then continue on to add Part 2 below.
Part 2
Find a recent article on the genetic epidemiology of a disease that interests you such as cancer, cystic fibrosis, hemophilia, birth defects, Down Syndrome, Tay-Sachs, Sickle Cell, Huntington’s, MS, etc.)
Write a short summary of the article defining the disease, and its impact on public health, and include the following information (if available):
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