Cardiovascular disease is the most common cause of adult morbidity and mortali

 
Cardiovascular disease is the most common cause of adult morbidity and mortality, accounting for 31% of deaths worldwide. The most common vascular system disorder is hypertension, defined by the American College of Cardiology and the American Heart Association (AHA) as blood pressure >130/80 mm Hg.
How do antihypertensive medications interact with determinants of cardiac output and peripheral resistance to reduce blood pressure?
What are the most common complications of untreated or undertreated hypertension?