In recent years, there has been a growing recognition of the intricate relations

In recent years, there has been a growing recognition of the intricate relationship between genetic predisposition and environmental factors in the development and progression of chronic diseases. Drawing upon current literature and your own research, construct a detailed analytical framework outlining the key genetic markers associated with a specific chronic disease of your choice. Subsequently, critically evaluate how environmental influences, such as lifestyle, diet, and exposure to pollutants, interact with these genetic factors to modulate disease risk and clinical outcomes. Provide examples and discuss potential therapeutic implications arising from a deeper understanding of this interplay.