My PICO Question: For adults over 65 years of age, who have obstructive sleep ap

My PICO Question:
For adults over 65 years of age, who have obstructive sleep apnea with cerebrospinal fluid alzheimers related biomarkers compared to those with no obstructive sleep apnea with no cerebrospinal fluid alzheimers biomarkers at increased risk for developing alzheimers disease over the course of one year?
I do not have a rubric for the second portion just need two to two and a half pages devoted to research findings and half a page for the conclusion.
I have three approved research articles that I’m attaching that have to be discussed in three seperate paragraphs. thank you so much!