Category: Nutrition

summarize an article of your choice from this website https://quackwatch.org/ in 1-3 pages, very easy, will take a short amount of time

1-discussio part
2-conclusion
i already attach the introduction file with litreture review and the file of result
also the guide from my prof to write this part ( discussion template ) .

professional work is needed

Week 14 discussion. Word document attached with questions.
From the Professor:
The HPAT axis is affected by any stressor: environmental, physiological, neurological- even a stressful thought upregulated the HPAT axis.
Chronic stress may produce subclinical hypothyroidism. Chronic stress decreases the effectiveness of glucocorticoid receptors-rendering them glucocorticoid resistant (similar to insulin resistance) –> upregulating inflammation. Increased inflammation –> ^ Reactive Oxidative Species–> less ATP production in mitochondria. Wonder why patients/clients who have sustained stress also complain of myalgia/arthralgia as well as fatigue??? Chronic stress also results in dysbiosis–> leading to decreased production of healthy neurotransmitters serotonin and dopamine–> anxiety /depression. This anxiety/depression then leads to more stress–> more dysbiosis–> less healthy neurotransmitters–> increased anxiety/depression–> and now a downward spiral. Prolonged stress places the body in fight/flight and more glucose is released into the blood stream to travel to the muscles so the patient/client can “run away from the saber tooth tiger”–> leading to hyperglycemia. Prolonged hyperglycemia–> ^^ inflammation.

Final Research design paper.
I have attached what I have so far.
My paper needs to include the following:
1. Introduce the significance of your topic
2. Background and literature review
3. Research questions, hypothesis and study design
4.Expected results and interpretation
5.Discussion on strength, shortness of the study
6.Potential application
7.Question unanswered, future research direction
Most of the details are present.
Please help me organize my original research design paper. I need more background information, discussion on strengths and limitations, and anything else you think my paper needs to ensure the paper details listed are included. You can add info to the paper to complete the final project.
The project is an original research design paper utilizing the sources/references noted.
Summary
The research design including the finalized RQ and hypotheses (and a brief summary of literature review to support the hypothesis), the study design (please make a flowchart* on this), subjects, inclusion & exclusion criteria, diet, treatment or intervention, procedure, variables and measurements, required resources including housing, equipment, human resources, fund, etc. Make sure you will think thoroughly and make a realistic and applicable plan.
PowerPoints to include:
For the presentation, it will be about the key points of your Research Design project to share with the class. You may include the following:
1. Introduction/Background
2.Research Need in the topic based on the literature review, and the Research Question (RQ) you selected for the project, and a hypothesis if applied
3.Methods and research design to address the RQ (with the flowchart),
4.Measurements for variables and your plan to analyze data for the RQ
5.A discussion
Note: You are encouraged to use more visuals, like tables, figures, diagrams (including the flowchart), etc, and use minimum words but present the information.

Answer all parts of the following 8 questions about your DWP Report in a typed paper. For ease of grading, please label each section of your paper with the headings Q1-Q8 as listed below.

I have uploaded a file containing the teacher’s instructions, please follow them exactly. Thank you!

There are four parts to completing this case study:
Part 1: Healthy Body WeightExamining your energy balance and factors that affect your appetite.Part 2: Breaking Bad HabitsExamining your unhealthy eating behaviors and developing a plan to break them.Part 3: Physical ActivityExamining your level of fitness and developing a plan to increase it.SummarySummarizing your plan for gaining or maintaining a healthy lifestyle.To receive full credit, all answers must be typed and in complete sentences to receive full credit. You will be graded for detail and specific information. Provide details that demonstrate your knowledge of nutrition and a healthy lifestyle. Listing, bulleting, or short answers are not acceptable.
Remember to use full sentences and paragraphs when answering all parts. A well-formed paragraph consists of at least three proper sentences. A proper sentence is a complete idea and consists of at least one noun and one verb

In a 3-page paper, written in APA format using proper spelling/grammar, address the following:
Define malnutrition and identify a specific disease that can result from it.
Perform library research about the selected disease, and explain its physiological effects on a person’s body.
Describe the relationship between specific foods/nutrients and the disease. Use the questions below to guide your response.
Does research indicate that a lack of specific foods/nutrients increase a person’s chance of contracting the disease?
Are there specific foods/nutrients that should be avoided by an individual afflicted with the disease?
How do specific foods/nutrients work physiologically within the body to help combat the disease?
Evaluate nutritional recommendations to help combat the disease.
Cite at least 3 credible references and present the resources in APA format on the References page

Below I will provide you with the professors recommendations on every part of the paper. Please make the corrections. Attached is the paper and rubric. Thanks for your hard work!
Feedback Week 4: Capstone Case Entry: Relevant Health History, AMQ
please include alcohol history.
Feedback for Week 5: Capstone Case Entry Relevant Diet Hx, and HAQ score and MSQ
Michelle- excellent- agree- need to know type of fluid intake especially w/ symptoms that may be associated with diabetes
Feedback for Week 6: Capstone Case Entry Relevant Diet Intake
Michelle- good diet intake synopsis. Place your dietary recommendations later in your therapeutic plan section of the capstone
Feedback for Week 9: Capstone Case Entry Lab Tests
Michelle- good selection odf testing.
Also consider adding a fasting insulin level to rule out insulin resistance.
Consider a Vit C level Vit C is needed to produce proline and proline is neede to make connective tissue for healing.
Feedback for Week 11: Capstone Case Entry Treatment/Therapeutic Plan
Michelle- excellent comprehensive therapeutic plan. In agreement w/ diet and supplements/actiuvity/stress management.
Fluids???
Stress also ^’s hepatic glucose release.
Feedback for Week 12: Capstone Case Entry Progress/Outcomes/Reevaluation Parameters
Michelle- good job
what about adding a food diary for tracking?

Please continue the outline you provided for me previously and elaborate on the points you suggested. I will post the information here as well as attach a word document. Thank you! Please write directly in the word document in another color so I can see the work. Thank you again
2. Drug-Induced Nutrient Depletion (DIND)
I. Overview of DIND
A. Introduction to the concept of drug-induced nutrient depletion as a common yet often overlooked complication of pharmacotherapy, specifically with prolonged metformin use.
II. Nutrients Affected by Metformin
A. Detailed enumeration of nutrients that metformin has been documented to deplete, focusing on Vitamin B12, Folate, and Coenzyme Q10 as the primary examples.
VII. Evidence of Depletion
A. Synopsis of evidence from clinical studies and research that substantiate the depletion of these nutrients, referencing the duration and dosage of metformin treatment that correlates with significant decreases in serum levels.
VIII. Physiological Mechanism of Depletion
A. Explanation of the biological mechanisms by which metformin interferes with the absorption and metabolism of these nutrients, such as the alteration of gut microbiota or interference with intrinsic factors for Vitamin B12 absorption.
IX. Clinical Consequences of DIND
A. Exploration of the potential health implications of this nutrient depletion, such as neuropathy or anemia from Vitamin B12 deficiency, and the importance of monitoring and managing these conditions.
X. Management Strategies
A. Brief overview of recommended strategies to mitigate DIND, including dietary supplementation, dosage adjustment, and regular monitoring of nutrient levels in patients on long-term metformin therapy.
3. Herb-Drug Interaction
I. Introduction to Interactions
A brief introduction to herb-drug interactions, emphasizing their potential impact on the efficacy and safety of metformin treatment.
II. Common Interactions
A. St. John’s Wort
Exploring possibility that St. John’s Wort may trigger the activation of enzymes that break down drugs, potentially diminishing the effectiveness of metformin (4).
B. Ginseng
Discuss how ginseng may affect blood glucose levels and potentially alter metformin’s blood sugar control (4).
III. Mechanisms of Interaction
A. Enzymatic Induction
Examining how certain herbs can induce metabolic enzymes, thus accelerating metformin clearance (5)
B. Alteration of Drug Transport
Assessment of how herbal compounds may interfere with drug transporters, affecting metformin absorption and distribution (5).
IV. Clinical Outcomes
A. Risk of Hypoglycemia or Hyperglycemia
Evaluating the risk of altered glycemic control due to herb-drug interactions.
B. Modification of Treatment
Considerations for modifying metformin therapy in the presence of significant herb-drug interactions.
V. Evidence and Research
A. Case Studies
Summary of case studies illustrating real-world examples of metformin and herb interactions.
B. Research Findings
Overview of research studies investigating the pharmacokinetics and pharmacodynamics of metformin when used concurrently with specific herbs.