Examine the 2 pairs of proteins below. In each case, these are enzymes that cata

Examine the 2 pairs of proteins below. In each case, these are enzymes that catalyze the
same reaction in different species. The question is: are they related or not? i.e. Are the
structures essentially the same? Often you can get similar reactions from proteins that
evolved from a common ancestor (e.g., trypsin and chymotrypsin). Sometimes the same
reaction can be catalyzed by proteins with very different evolutionary origins and with very
different structures (e.g., trypsin and subtilisin). Your job is to decide if these proteins have
fundamentally different folds or if they have basically the same fold. Briefly justify your
answer (≤5 sentences).
1. Aminopeptidases from a mammal (PR1A) and the malaria parasite (PR1B)
2. Bisphosphoglycerate mutase from a mammal (PR2A) and the toxoplasma parasite
(PR2B)