Advanced Pharmacology Case Scenarios: Prescribing and Clinical Decision-Making

WEEK 4 ASSIGNMENT (covers weeks 3-6)

SCENARIO 1

What are the errors in the following prescriptions (1 per prescription)? Rewrite each prescription correctly. What is each medication classification? What is the mechanism of action (MOA)?

  • Ubrelvy 200 mg PO at onset of migraine #30 0 RF
  • memantine/donepezil (Sinemet) 7/10 mg po once daily #30 1 RF
  • Stalevo 200 mg po TID #90 2 RF
  • levothyroxine 137 mg PO daily #30 3 RF
  • omeprazole (Protonix) 40 mg PO daily before breakfast #30 3 RF

 

SCENARIO 2

AL a 46-year-old female presents to clinic with chief complaint, “I get short of breath and wheeze almost every night. I also have a cough that wakes me up 2-3 times a week.” Her symptoms have been present almost 3 months. She has no prior hospitalizations or ED visits; no smoking history and no significant occupational exposures. She takes cetirizine for seasonal allergic rhinitis. NKDA. CBC normal, BP 114/68, HR 88, RR 18, SpO₂: 97%, spirometry: FEV₁ 70% predicted, FEV₁/FVC 0.65, reversibility testing: FEV₁ improves by 15% after albuterol inhalation, Peak Expiratory Flow (PEF): 65% of personal best. What is your diagnosis and treatment plan? How would you monitor treatment and what patient education would you provide?

 

SCENARIO 3

LV is a 9-year-old female that experiences brief staring episodes lasting ~10 seconds, occurring multiple times per day. Otherwise healthy, NKDA. Normal CBC, CMP, LFTs. She has been diagnosed with typical absence seizures. As her provider, your task is to initiate pharmacologic therapy. Write a complete medication order for LV, include monitoring parameters and patient/caregiver education points relevant to the medication and seizure management.

 

 

SCENARIO 4

TY is a 65-year-old male with poorly controlled type 2 diabetes and exhibits challenges with adherence. Current medications include donepezil 5 mg po qhs and losartan 50 mg po daily. His lab work today includes: BG 190 mg/dL, A1C  8.5%, K⁺ 4.1,  Cr 1.9, eGRF 26, BP 125/76.

Which of the following would you prescribe:

  • canagliflozin (Invokana) 100 mg PO daily
  • exenatide (Byetta) 5 mcg SC twice daily
  • glimepiride 1 mg PO daily
  • glyburide 2.5 mg PO daily
  • metformin 500 mg PO daily
  • semaglutide (Ozempic) 0.25 mg SC once weekly
  • sitagliptin (Januvia) 50 mg PO daily

 

What is the classification and MOA of the drug you selected? What education would you provide and how would you monitor the effectiveness of the treatment plan? What is his goal A1C and blood pressure?

APA References for the scenarios are within past 5 years and include the appropriate clinical practice guideline if applicable.

Written medication orders include all 5 aspects required for a valid order. The order is complete, accurate, and appropriate.

Struggling with where to start this assignment? Follow this guide to tackle your assignment easily!

This Week 4 assignment assesses your ability to identify prescribing errors, apply evidence-based treatment guidelines, and write complete, legally valid medication orders. Follow the steps below carefully to ensure you meet all grading criteria across Scenarios 1–4.


Scenario 1: Prescription Errors, Corrections, and Pharmacology

Step 1: Identify the Prescription Error

For each prescription, identify one clear error (e.g., incorrect dose, incorrect drug name, wrong units, brand/generic mismatch, or unsafe dosing).

Step 2: Rewrite the Prescription Correctly

Rewrite each prescription using all five required components of a valid medication order:

  1. Medication name (generic preferred)

  2. Dose

  3. Route

  4. Frequency

  5. Quantity and refills

Ensure the corrected prescription is safe, accurate, and appropriate.

Step 3: Identify Drug Classification

State the pharmacologic class for each medication (e.g., CGRP antagonist, cholinesterase inhibitor).

Step 4: Explain the Mechanism of Action (MOA)

Briefly explain how each medication works at the physiological or receptor level.


Scenario 2: Adult Asthma Diagnosis and Management

Step 1: Establish the Diagnosis

Use the patient’s history, spirometry, reversibility testing, and symptoms to identify the most appropriate asthma classification.

Step 2: Develop a Treatment Plan

Select evidence-based pharmacologic therapy aligned with current asthma guidelines. Include both:

  • Controller medication(s)

  • Rescue medication(s)

Step 3: Monitoring Plan

Explain how you would monitor:

  • Symptom frequency

  • Lung function

  • Medication adherence and response

Step 4: Patient Education

Provide education on:

  • Inhaler technique

  • Trigger avoidance

  • When to seek urgent care

  • Importance of adherence


Scenario 3: Pediatric Absence Seizures

Step 1: Select First-Line Pharmacologic Therapy

Choose an appropriate first-line antiepileptic medication for typical absence seizures.

Step 2: Write a Complete Medication Order

Write a fully valid medication order including:

  • Drug, dose, route, frequency

  • Quantity and refills

  • Appropriate pediatric dosing

Step 3: Monitoring Parameters

Include necessary monitoring such as:

  • Lab tests

  • Adverse effects

  • Seizure frequency and response

Step 4: Patient and Caregiver Education

Provide education on:

  • Medication adherence

  • Side effects

  • Seizure safety precautions

  • When to seek medical attention


Scenario 4: Type 2 Diabetes With CKD and Adherence Challenges

Step 1: Evaluate Medication Options

Critically evaluate each listed medication option using:

  • Renal function (eGFR)

  • Hypoglycemia risk

  • Adherence considerations

  • Cardiovascular and renal benefit

Step 2: Select the Most Appropriate Medication

Choose one medication that is safest and most effective for this patient’s clinical profile.

Step 3: Classification and MOA

Identify the drug’s class and clearly explain its mechanism of action.

Step 4: Patient Education and Monitoring

Discuss:

  • Medication administration

  • Potential side effects

  • Monitoring parameters (A1C, renal function, glucose trends)

Step 5: Treatment Goals

State the patient’s:

  • Goal A1C

  • Blood pressure target

Ensure these align with current diabetes guidelines.


APA References and Writing Expectations

  • Use APA format

  • References must be within the past 5 years

  • Include current clinical practice guidelines where applicable

  • Maintain professional grammar, clarity, and organization

  • Ensure all medication orders are complete, accurate, and appropriate


Recommended Evidence-Based Resources

You may use the following authoritative sources:

 

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