Please write a discussion post reply of 450 words to the following post. Must h

Please write a discussion post reply of 450 words to the following post. Must have at least 2 scholarly peer-reviewed sources using APA format. Sources must be within the last 5 years. Must include one biblical integration that is NOT to be listed as a resource. Original post instructions are listed here: After reading the Read: Nursing Management of the Patient with Multiple Sclerosis and Read: What are the Levels of Evidence? in the Learn section, answer the following questions: Are the guidelines based on evidence? Using the Levels of Evidence Pyramid what is the evidence rating? Would you use the guideline based on the evidence provided? Is there a better approach? How does the evidence you select for your literature review paper fit into this evidence rating?
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In nursing management for patients with multiple sclerosis, guidelines should ideally be based on the highest levels of evidence available, considering the complexity of the condition and the potential impact of interventions on patients’ quality of life. In “Nursing Management of the Patient with Multiple Sclerosis,” all the information gathered was based on evidence. The American Association of Neuroscience Nurses, Association of Rehabilitation Nurses, and the International Organization of Multiple Sclerosis Nurses all worked together to compile the information they had about Multiple Sclerosis (MS) and put together a Clinical Guideline publication to be used by nurses caring for patients with MS. MS is a chronic autoimmune neurological disorder in which the immune system attacks the protective covering of nerve fibers, leading to inflammation, damage, and communication breakdown between the brain and the rest of the body (Oh et al., 2018). This disruption can cause many symptoms, including fatigue, difficulty walking, numbness or weakness in limbs, vision problems, and cognitive challenges. MS varies in severity and progression, with relapses and remissions being common. It primarily affects young adults and is a lifelong condition that requires ongoing management and treatment.
The Levels of Evidence Pyramid is a hierarchical representation used in evidence-based practice to categorize different research studies based on their methodological rigor and the strength of evidence they provide. The pyramid organizes research from lower-quality proof at the bottom to higher-quality evidence at the top (Wormald & Evans, 2018). Most of the recommendations within the article were Level 3 recommendations, which Class III and IV evidence support. According to the article, Class III evidence is based on qualitative studies, case studies, or series. Class IV evidence comes from reports of expert committees and expert opinions of the guideline panel, standards of care, and clinical protocols. This is lower than Level 1 and Level 2, which are based upon randomized controlled trials without significant limitations or meta-analysis and randomized controlled trials with necessary rules and observations (Melnyk & Fineout-Overholt, 2022).
I would use this guideline as it has a great deal of information on MS, and the authors of the policies are at the forefront of MS treatment. Obtaining Level 1 evidence, represented by high-quality randomized controlled trials (RCTs), is challenging due to ethical considerations, resource-intensive requirements, difficulties in participant recruitment and blinding, the unpredictability of results, the need for large sample sizes, long follow-up periods, and the potential for publication bias (Dobson & Giovannoni, 2019). These challenges can limit the feasibility of conducting RCTs, making it difficult to achieve the highest standard of evidence in healthcare research. The literature I have selected for my literature review is mostly Level 2 and 3-based evidence. Soft-shell helmet covers are a relatively new practice, and there is not a great deal of literature on how much it reduces the incidence of Chronic Traumatic Encephalopathy (CTE) in adults. Level 1 evidence is considered the gold standard but challenging to obtain, as explained earlier in this post. Level 1 evidence, akin to the solid foundation of a structure, reflects the pinnacle of research integrity and reliability in healthcare. Similarly, in Matthew, Jesus teaches about building on a rock, symbolizing a firm foundation that withstands trials, and aligning with basing decisions on robust evidence to ensure lasting and trustworthy outcomes (ESV, 2016, Matthew 7:24).