A 28 year old male presents with opioid dependency. He is not in treatment at t

A 28 year old male presents with opioid dependency. He is not in treatment at the present time, and is exhibiting severe withdrawal symptoms.
Compare and contrast the efferent and afferent nerve pathways.
What is nociception?
What is somatogenic pain?
What is hyperalgesia? How does Naloxone work?
At least one scholarly reference within last 5 years