1) Each biomarker has own biological half-life. Discuss the impact of biomarker’s half-life on diagnosis or monitoring. How can biomarker’s half-life be used to guide sampling time and frequency? Provide THREE examples in your answers.
2) Exposure to heavy metals (e.g., lead, arsenic, mercury, antimony, cadmium) can be assessed by methods that are very different from methods used for organic chemicals (e.g., benzene). Discuss appropriate assessment methods of detection and quantification.
3) What is a biorepository or biobank? What are some major ethical and scientific considerations in biobanking of biological samples? Discuss recommendations/best practices for long-term storage of biological samples (e.g., urine and blood). Why are these important?
Your response must be a maximum of 2 pages (total), with 0.75-inch margins on all sides, single-space, font Arial 11 or Times New Roman 12. You can include figures and/or tables, but they should be designed by you or cited if taken from the literature. No more than 2 figures and 2 tables are allowed. Figures and tables count towards the page limit and must be embedded within the main document. References are not included in the page limit and in-text citations must be in numerical format. Run Turnitin to avoid similarities prior to submission (<30% similarities accepted).
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