Similar to the PFD we constructed in class 1-2 weeks ago (depending on when you
Similar to the PFD we constructed in class 1-2 weeks ago (depending on when you start this assignment), in the manufacture of pharmaceuticals, most active pharmaceutical ingredients (APIs) are made in solution and then recovered by separation. Acetaminophen, a pain-killing drug commercially marketed as Tylenol®, is synthesized in an aqueous solution and subsequently crystallized. The slurry of crystals is sent to a centrifuge from which two effluent streams emerge: (1) a wet cake containing 90wt% solid acetaminophen (MW = 151 g/mol) and 10wt% water and (2) a highly dilute aqueous solution of impurities and acetaminophen that are discharged from the process. The wet cake is fed to a dryer where the water is completely evaporated, leaving the residual acetaminophen solids bone dry. If the evaporated water were condensed, it’s volumetric flow rate would be 50 L/h.a. Draw a flowchart (PFD) of this process.b. If the process runs 24h/day, 320 days/year, determine the annual production of acetaminophen (tons/year).

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