A‌‍‍‍‌‍‍‌‌‍‍‍‌‍‍‍‍‌‍‍nswer both discussion questions. 1.Every experiment in the

A‌‍‍‍‌‍‍‌‌‍‍‍‌‍‍‍‍‌‍‍nswer both discussion questions. 1.Every experiment in the United States has to be registered with ClinicalTrials.gov. Visit the clinical trials website. Select a disease that is of interest to you. Search that disease in clinical trials. Select a clinical trial that is currently going on with this disease. In 300 – 500 words, describe the clinical trial, inclusion, and exclusion criteria. What phase is this trial? Is it single or double blind? What methods does it use (Random Clinical Trial, Community Intervention, Pre/post method or single group design). Based on what you have read in the textbook, what do you think are the limitations of this trial based on what is written in the clinical trials summary of the methods. 2. Please review this Excel spreadsheet: Week 2 Epidemiological Examples In your post, you are to select a disease that no one else has selected. You can post early in the week to reserve your disease and then just reply to your original pos‌‍‍‍‌‍‍‌‌‍‍‍‌‍‍‍‍‌‍‍t when your material is done. Answer the following questions with your initial post. 1. What disease did you select? 2. Find two different incidence rates for this disease. This can be either the rates of the disease in two different countries, age groups, ethnicities, occupation, or any other classifier that might be important to your disease. Provide the two different rates here. Cite your source. 3. Select a screening test or a confirmatory test for your disease. Report on what the sensitivity and specificity percentages are and cite your source. Also, provide the cost of the test. 4. Using the method outlined in the excel document determine the PPV and NPV of using both screening tests in the two populations you selected. 5. How much did each true positive cost? 6. Does it make sense to implement mandatory screening in either population? Why or why not? Readings: Gordis, L. (2014). Epidemiology, 5th edition with New York: Elsevier Health Sciences‌‍‍‍‌‍‍‌‌‍‍‍‌‍‍‍‍‌‍‍.

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